Fall 2000 Annual Meeting, Los Angeles, CA
12 – 17 November 2000
Process Research and Innovation Area (12a) Sessions
274: Chemists and Chemical Engineers: An Integrated Team for Process Development
Chair: Prof. Ka Ng, Hong Kong Univ. of Science & Technology,
Co-chair: Aaron Sarafinas,
Review of the session
The Process Development Division of the AIChE sponsored a session on the
collaboration between chemists and chemical engineers at the annual AIChE
meeting in Los Angeles in November 2000. The session was attended by over
50 chemical engineers and a few chemists. In addition to the six (6)
presentations from highly respected industrial practitioners, the audience
was invited to share their thoughts on this subject. Following is a summary
of their comments, which can be classified into four categories.
- Personal Experiences
- ChE: The chemists do not balance their reactions.
- ChE: The chemists do not tell me what the impurities are and their amounts.
- Chemist: The reaction works just fine in the laboratory. Certainly, it should work in the pilot plant.
- ChE: I wish the chemists took those data under a different set of conditions.
- ChE: There are no stability data over time.
- ChE: We have 16 hour holds.
- Chemist and ChE: You took my job away.
- Chemist: Engineers are above learning reactions.
- Chemist: Engineers won't learn chemistry.
- ChE: They look at scaleup as simply a bigger laboratory.
- ChE: Every reaction system is scaled by statistical design with no modeling.
- ChE: They often blame the use of different techniques for scaleup troubles, not heat or material balance.
- ChE: Chemists do not appreciate the importance of physical properties.
- Chemist and ChE: Each trying to become the other.
- ChE: Chemists focus only on yield.
- Barriers to a successful interdisciplinary team
- Lack of appreciation of the difference in objective of the other discipline.
- Lack of appreciation of the time and effort requirements of the other discipline.
- Geography: proximity vs. globalization in process development.
- Organization structure is not conducive to a team effort.
- Lack of shared vision - "pettiness prevails".
- Reward structure: patents are granted for chemistry but not for process.
- Benefits to a successful interdisciplinary team
- Reduced time-to-market.
- The best possible process the first time.
- Elimination of "handoffs".
- How do we move forward?
- Join Process Development Division!
- Devise workflow procedures for the chemist-chemical engineer team.
- Bring chemists and chemical engineers together in the same location.
- Seek support from senior management.
- Clearly define roles but without putting people into "boxes" and discouraging individual initiatives.
- Build rapport socially and informally.
- Management should appreciate different functions in process development and continue to facilitate collaborations.
- Encourage development of interpersonal skills.
- Work with the ACS group.
Presentations in this session
- 274a: Development of a New Resin Process for Toner Application,
Emily L. Moore (speaker), Allan K. Chen, Arthur Helbrecht,
Patricia Burns, Lu Jiang, Martina St. Hilaire, Abdisamed Sheik-Qasim,
Dave Kurceba, Chieh-Min Cheng, Xerox Corporation
- 274b: An Integrated Approach to Agricultural Intermediate Process
Development, Renee C. Roemmele (speaker), Aaron Sarafinas, James
C. Eagleton , Rohm and Haas Company
- 274c: Partnering for Success: ACE Teams in Drug Process
Development, Kathleen P Barton (speaker), Erwin A. Irdam, Christine
B. Seymour, Mark A. LaPack, James R. Behling, Pharmacia Corporation
- 274d: The Development of a Novel Process, from Ideas to Patents
Lionel O'Young (speaker), Mitsubishi Chemical Company
- 274e: Hi-O Silver --- Away: Teams and Process Development,
Jonathan H. Worstell (speaker), Shell Chemical Company
- 274f: Helping Chemists Understand How ChE's Think (and vice versa)
Thomas A. Kenat (speaker), KenaTech Process Engineering
- 274g: Discussion: Working Together Brings Value by session Chairs
Pilot Plants Area (12b) Sessions
276: Lab and Pilot Plant Instrumentation
Chair: John Iverson, Parke-Davis Co.
Co-chair: Michael VonDeak, Pharmacia,
- 276b: Multidimensional On-line Process Gas Chromatography Based on
a Single GC with Dual Independently Controlled Ovens,
Jacques F. Nicole (speaker), Patrick L. Mills, Thomas M. Delaney,
E.I. duPont de Nemours & Co
- 276c: Simulation of a Sieve Plate Column Using a Nonequilibrium
Stage Model, Cintia Soares, State University of Campinas;
António Andrea Chivanga Barros, University of Blumenau;
Maria R. Wolf-Maciel (speaker), UNICAMP
- 276d: FBRM and PVM for Particulate Process Optimization, Scale-up,
and Tech Transfer, Richard P. Becker (speaker), Lasentec
- 276e: Experimental Measurement of Relative Volatilities by Inert
Gas Stripping, Diane Hildebrandt (speaker), Shehzaad Kauchali,
Camilla Neilsen, David Glasser, University of the Witwatersrand
275: Modernizing Pilot Plant Facilities
Chair: Dave Edwards, Zeton Inc.,
Co-chair: Carol Calvano, Mobil Technology Co.,
- 275a: Repair, Relocate or Rebuild? A Discussion Of Options For
Older Pilot Plants, Richard P. Palluzi (speaker), ExxonMobil
Chemical Company
- 275b: In-Kind Batch Vessel Replacement -- There can Never be
Enough Planning, John Corn (speaker), Vincent Williams, Ashland
Specialty Chemical Co.
- 275c: Control System Upgrade in a Pilot Plant Facility,
Sean Murray (speaker), Ruud T. Mennink, Zeton B.V.
- 275d: Non-Glovebox Containment of Solids, Ephraim Bassan,
Merck & Co., Inc.
Technology Transfer (12c) Sessions
277: Technology Transfer in Food, Pharmaceuticals, and Fine Chemicals
Co-Sponsored with Division 15 (Food, Pharmaceutical & Bioengineering Division)
Chair: Cawas Cooper, Air Products & Chemicals, Inc.,
Co-chair (Group 15): Clint Pepper, DepoTech, Inc.,
- 277a: The Role of Modeling in Process Development and Technology
Transfer, Demetri P. Petrides, Alex Koulouris, INTELLIGEN, INC.;
Perry Lagonikos (speaker), Schering-Plough Research Institute
- 277b: Solvent Selection for Drug Development, Peter M. Harper
(speaker), Jens Abildskov, Martin B. Nielsen, Rafiqul Gani, Technical
University of Denmark; Petr Kolar, Akio Tsuboi, Mitsubishi Chem. Corp
- 277c: Developing and Licensing NEODOX: An Example of Reducing
Cycle Time, Jonathan H. Worstell, Shell Chemical Company
- 277d: A Methodology for the Development of Pharmaceutical
Processes Under Uncertainty, David B. Johnson (speaker),
I. D. L. Bogle, University College London
- 277e: Inherently Safe and Sustainable Pharmaceutical Technology
Relocation, Jodi L. Moe (speaker), Pharmacia
- 277f: An Experience with a Stage Gate Process during Development
and Commercialization of New Technologies for Fine Chemicals,
O. Mikus, AECI Ltd.